PROCESS FOR PREPARING N,N-DISUBSTITUTED CARBOXYLIC ACID AMIDES

摘要

The method for preparing N,N-disubstituted carboxylic acid amides used in pharmaceutical materials and agricultural chemicals comprises: (a) dissolving 2.49g of 2-(3-methoxy)-thienylmethyli dene in 15ml of benzene and dissolving 2.48g of trichlorosilane in 5ml of benzene; (b) mixing the above mixtures and adding chloroacetylchloride solution to the mixture; (c) agitating the above mixture at room temperature for 2 hrs and removing components with low boiling point; (d) dissolving the residual viscous solution in benzene and washing benzene solution with water; (e) drying washed viscous solution under vaccum to obtain 3.30g of solid product.