| 发明名称 |
Transglutaminase inhibitors |
| 摘要 |
The present invention is directed to certain 3,5 substituted, 4,5-dihydroisoxazoles, and methods for their use. These compounds are transglutaminase inhibitors, and are particularly effective in the inhibition of epidermal transglutaminase and the treatment of acne.
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| 申请公布号 |
US4929630(A) |
申请公布日期 |
1990.05.29 |
| 申请号 |
US19890404791 |
申请日期 |
1989.09.08 |
| 申请人 |
SYNTEX (U.S.A.) INC. |
发明人 |
CASTELHANO, ARLINDO L.;DEYOUNG, LAWRENCE M.;KRANTZ, ALEXANDER;PLIURA, DIANA H.;VENUTI, MICHAEL C. |
| 分类号 |
C07D261/04;C07D413/12;C07K5/06;C07K5/065 |
主分类号 |
C07D261/04 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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