发明名称 HUMAN INSULIN ANALOGUES
摘要 1989-12-06, ATS/KGF 3343.010-DK Human insulin analogues having a positively charged amino acid residue, i.e. Lys or Arg, in position B28, i.e. in position 8 in the B-chain calculated from ¢GlyB20!, and optionally being further modified in the C-terminal end of the Bchain from ¢PheB24! to the C-terminal amino acid residue and optionally A21 and/or B3 being different from Asn as well as insulin preparations containing the human insulin analogues are provided.
申请公布号 CA2006578(A1) 申请公布日期 1990.06.23
申请号 CA19892006578 申请日期 1989.12.22
申请人 NOVO-NORDISK A/S 发明人 BALSCHMIDT, PER;BRANGE, JENS J. V.
分类号 C12N15/09;A61K9/08;A61K9/107;A61K38/00;A61K38/28;A61P3/08;A61P3/10;C07K7/00;C07K14/575;C07K14/62;C12N15/17;C12P21/02;C12P21/06;C12R1/865;(IPC1-7):C12N15/17 主分类号 C12N15/09
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