PREPARATION OF NOVEL SUBSTITUTED 2,4-DIAMINO-5-BENZYL-PYRIMIDINES FOR USE AS MEDICAMENTS WITH AN ANTIMICROBIAL ACTIVITY

摘要

The 2,4-diamino-5-benzylpyrimidines have antimicrobial activity and are in particular suitable for inhibiting the growth of mycobacteria. They display pronounced synergistic activity in combination with inhibitors of the diaminodiphenyl sulphone, ring-substituted 4-aminodiphenyl sulphone or ring- and/or nitrogen-substituted diaminodiphenyl sulphone types. ……