发明名称 Serotonin antagonist.
摘要 Use of a compound of the formula (I) <CHEM> wherein R<1> is hydrogen, halo, C1-C5 alkoxy or C2-C6 dialkyl amino; R<2> is hydrogen, halo or C1-C5 alkoxy; R<3> is hydrogen, hydroxy, -O-(CH2)n-COOH or -O-CO-(CH2)l-COOH, wherein n is an integer of 1-5, and l is an integer of 1-3; R<4> is <CHEM> wherein R<5> and R<6> are each independently hydrogen or C1-C8 alkyl, and A is C3-C5 alkylene or C3-C5 alkylene substituted with carboxy; and m is an integer of 0-5, or a pharmaceutically acceptable salt thereof, for the preparation of a pharmaceutical formulation useful as a serotonin antagonist.
申请公布号 EP0398326(A2) 申请公布日期 1990.11.22
申请号 EP19900109336 申请日期 1990.05.17
申请人 MITSUBISHI KASEI CORPORATION 发明人 OSAKABE, MASANORI;HARA, HIROTO;TAMAO, YOSHIKUNI;KIKUMOTO, RYOJI
分类号 A61K31/135;A61K31/19;A61K31/215;A61K31/22;A61K31/225;A61K31/395;A61K31/397;A61K31/40;A61K31/445;A61P7/02;A61P9/00;A61P9/08;A61P9/10;A61P43/00;C07C217/18;C07C217/32;C07C219/06;C07D205/04;C07D295/08 主分类号 A61K31/135
代理机构 代理人
主权项
地址