| 发明名称 |
ILLUDIN ANALOGS AS ANTI-TUMOR AGENTS |
| 摘要 |
A method of inhibiting certain tumor cell growth in a subject is provided comprising contacting the tumor with a therapeutic amount of an illudin S or illudin M analog having the structure <IMAGE> wherein the analog is capable of inhibiting tumor cell growth without excessive toxicity to the subject and wherein R1 is hydrogen; R2 is methyl; and R3 is hydroxy. |
| 申请公布号 |
AU6729590(A) |
申请公布日期 |
1991.04.28 |
| 申请号 |
AU19900067295 |
申请日期 |
1990.10.02 |
| 申请人 |
UNIV CALIFORNIA |
发明人 |
MICHAEL J KELNER;TREVOR C MCMORRIS;RAYMOND TAETLE |
| 分类号 |
A61K31/12;A61K31/215;A61K31/22;A61K31/27;A61P35/00;C07C45/45;C07C45/46;C07C45/65;C07C45/67;C07C49/665;C07C49/67;C07C49/683;C07C49/727;C07C49/737;C07C49/747;C07C49/753;C07C49/755;C07C69/007;C07C69/757;C07C271/12 |
主分类号 |
A61K31/12 |
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