发明名称 |
PROCESS FOR PRODUCING PIRROLOQUINOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
摘要 |
<p>A compound of the formula: <CHEM> in which R<1> and R<2> are each hydrogen or lower alkyl, R<3> is aryl or heterocyclic group, each of which may be substituted by suitable substituent(s), R<4> is hydrogen, halogen or lower alkyl, A is methylene, methine, oxa, thia, sulfinyl or sulfonyl, Y is vinylene or ethylene, Z is a group of the formula: <CHEM> wherein R<5> is carboxy or protected carboxy, and R<6> is hydrogen or hydroxy-protective group, and the line of --- is a single or double bond, or pharmaceutically acceptable salts thereof, processes for their preparation and pharmaceutical comoositions comprising them as an active ingredient in admixture with a pharmaceutically acceptable carrier or excipient.</p> |
申请公布号 |
HUT55015(A) |
申请公布日期 |
1991.04.29 |
申请号 |
HU19900005089 |
申请日期 |
1990.08.21 |
申请人 |
FUJISAWA PHARMACEUTICAL CO. LTD.,JP |
发明人 |
MATSUO,MASAAKI,JP;MANABE,TAKASHI,JP;OKUMURA,HIROYUKI,JP;MATSUDA,HIROSHI,JP;FUJII,NAOAKI,JP |
分类号 |
C12N9/99;A61K31/475;A61K31/545;A61P3/06;A61P43/00;C07D;C07D471/06;C07D498/06;C07D513/06;C07F7/18;(IPC1-7):C07D471/06;A61K31/33;A61K31/435 |
主分类号 |
C12N9/99 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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