Process for production of 2-phosphated esters of ascorbic acid.

摘要

A process for the production of 2-phosphated esters of ascorbic acid by subjecting an ascorbic acid optionally protected at the 5- and 6-positions to phosphorylation with maintaining the concentration of the optionally protected ascorbic acid in a reaction mixture at less than 0.3 M and, if necessary, removing any protecting group is disclosed. 2-Phosphated ester of ascorbic acid can be produced with a good yield in an industrial scale by this process.