| 发明名称 |
2-piperidones as intermediates for 5-deaza-10-oxo- and 5-deaza-10-thio-5,6,7,8-tetrahydrofolic acids |
| 摘要 |
4-Deaza-10-oxo- and 5-deaza-10-thio-5,6,7,8-tetrahydrofolic acid derivatives are provided as agents useful for treatment susceptible neoplasms in mammals. Pharmaceutical formulations and intermediates are also provided.
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| 申请公布号 |
US5159079(A) |
申请公布日期 |
1992.10.27 |
| 申请号 |
US19910810990 |
申请日期 |
1991.12.20 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
PEARCE, HOMER L.;WINTER, MARK A. |
| 分类号 |
A61K31/505;A61P35/00;C07D211/76;C07D471/04;C07F7/18 |
主分类号 |
A61K31/505 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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