| 摘要 |
<p>Disclosed is a method and apparatus for forming a transdermal drug delivery device from a multilayer web (1) comprised of a backing layer (16), a drug-containing pressure sensitive adhesive layer (14), and a release layer (12) or liner in which cutting is progressively achieved along a line coplanar with the axes of a cutting roller (86) and anvil roller (92) counter-rotating in proximity to each other. Cutting is achieved completely through the web (10) about the periphery of the transdermal drug delivery device, while simultaneously achieving a scoring only of the release liner (12) without penetration of the pressure sensitive adhesive layer (14) or backing layer (16).</p> |
