| 摘要 |
<p>A compound of formula (I), wherein R1 is a hydrogen atom or a methyl group, R2 is a hydrogen atom or a negative charge, R3 is a hydrogen atom, a halogen atom, a hydroxyl group, a lower alkoxy group, a lower alkanoyloxy group, an amino group, an N-lower alkylamino group, an N,N-di-lower alkylamino group, a lower alkanoylamino group, an aroylamino group, a (lower alkylsulfonyl)amino group, a sulfamoylamino group, a cyano group, a nitro group, a group of -COOR4 (wherein R4 is a hydrogen atom or a lower alkyl group) or a group of -CON(R5)R6 (wherein each of R?5 and R6¿ which may be the same or different, is a hydrogen atom or a lower alkyl group, or R?5 and R6¿ form together with the adjacent nitrogen atom a heterocyclic group selected from the group consisting of an aziridinyl group, an azetidinyl group, a pyrrolidinyl group, a piperidyl group, a piperazinyl group, a 4-lower alkyl piperazinyl group and a morpholino group), A is a linear or branched lower alkylene group, X is a group of -N(R7)R8 (wherein each of R?7 and R8¿ which may be the same or different, is a hydrogen atom or a lower alkyl group) or a group of -N?+(R9)(R10)R11¿ (wherein each of R?9, R10 and R11¿ which may be the same or different, is a lower alkyl group), provided that when A is a linear lower alkylene group, R3 is other than a hydrogen atom; or a pharmaceutically acceptable salt or ester thereof.</p> |
