| 发明名称 | Glue composition for lung volume reduction | ||
| 摘要 | The present invention relates to methods and compositions for sealing localized regions of damaged lung tissue to reduce overall lung volume. The glue compositions provide a glue featuring an adhering moiety coupled to one or more other moieties including, for example, a cross-linkable moiety and/or one other adhering moiety. The methods and compositions of the invention find use, for example, in treating pulmonary conditions, such as emphysema. | ||
| 申请公布号 | USRE46209(E1) | 申请公布日期 | 2016.11.22 |
| 申请号 | US201514699818 | 申请日期 | 2015.04.29 |
| 申请人 | PneumRx, Inc. | 发明人 | Gong Glen;Dieck Ronald |
| 分类号 | A61K38/55;A61P11/00;A61K47/48;B82Y5/00;A61K38/57;A61K51/08 | 主分类号 | A61K38/55 |
| 代理机构 | Kilpatrick Townsend and Stockton LLP | 代理人 | Kilpatrick Townsend and Stockton LLP |
| 主权项 | 1. A method of reducing lung volume in a lung of a subject in need thereof, comprising: administering an effective amount of a glue composition to a localized region of damaged lung tissue of the subject, wherein the glue composition comprises a polyvinylalcohol polymer and a cross-linker, such that the polymer and cross-linker form a hydrogel in the lung, thereby reducing lung volume in the lung of the subject. | ||
| 地址 | Mountain View CA US | ||