| 发明名称 |
HETEROARYL CINNAMIC ACIDS AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS |
| 摘要 |
TITLE OF THE INVENTION HETEROARYL CINNAMIC ACIDS AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS Compounds having the formula I: <IMG> I are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.
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| 申请公布号 |
CA2125830(A1) |
申请公布日期 |
1994.12.24 |
| 申请号 |
CA19942125830 |
申请日期 |
1994.06.14 |
| 申请人 |
MERCK FROSST CANADA INC. |
发明人 |
FORTIN, REJEAN;GIRARD, YVES;GRIMM, ERICH;HUTCHINSON, JOHN;SCHEIGETZ, JOHN |
| 分类号 |
C07D309/10;C07D407/12;C07D409/12;C07D493/08;(IPC1-7):C07D493/08;C07D409/00;C07D335/02;C07D471/04;C07D309/06;C07D405/12;A61K31/19;C07D333/24;A61K31/33;C07D307/54;C07C59/68 |
主分类号 |
C07D309/10 |
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