| 摘要 |
Disclosed are deoxyfructonucleotides and dideoxyfructonucleotides represented by formula (I) which may be used as propagators and terminators in DNA extension reactions, wherein R<1> is H2PO3, H3P2O5, H4P3O7 or the salts thereof, or H; B is a naturally occurring nucleic acid base or synthetically modified nucleic acid base; R<2> is OR<3>, N3, Y-Biotinoyl, or NHC=O(CH2)nY-Biotinoyl; wherein: R<3> is H, alkyl, aralkyl, acyl or aroyl; Y is NH or O; n=1-10, and A is H or OH. |
