摘要 |
The invention relates to transglycosylase inhibitors whose chemical structure is related to that of the moenomycin antibiotics, to the preparation thereof by chemical synthesis and to the use thereof as pharmaceuticals. The transglycosylase inhibitors have the compound of the formula <IMAGE> in which R<1> to R<4> = hydrogen, R<5> = -OH, -OR<6> or <IMAGE> , R<6> = hydrogen, alkyl or aryl and R<7> and R<8> are, independently of one another, hydrogen or alkyl.
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申请人 |
HOECHST AG, 65929 FRANKFURT, DE |
发明人 |
WELZEL, PETER, PROF. DR., 44789 BOCHUM, DE;MUELLER, DIETRICH, DR., 44801 BOCHUM, DE;LUEMING, JOACHIM, 58256 ENNEPETAL, DE;MOELLER, UWE, DR., 44894 BOCHUM, DE |