An inclusion complex of diclofenac, preferably as diclofenac sodium, and an unsubstituted beta-cyclodextrin has the formula 1 molecule of diclofenac to 1 molecule of the unsubstituted beta-cyclodextrin and preferably from 5 to 11 water molecules. The inclusion complex may be formulated as a pharmaceutical composition.
申请公布号
CA2133885(A1)
申请公布日期
1995.04.09
申请号
CA19942133885
申请日期
1994.10.07
申请人
SOUTH AFRICAN DRUGGISTS LIMITED
发明人
BODLEY, MARK D.;CAIRA, MINO R.;GLINTENKAMP, LUETA A.;GRIFFITH, VIVIENNE J.;NASSIMBENI, LUIGI R.;NICHOLSON, DOUGLAS G. M.;PENKLER, LAWRENCE J.;VAN OUDTSHOORN, MICHAEL C. B.
