发明名称 Process for producing ortho-isopropylated phenol derivatives
摘要 This invention relates to the process for producing ortho-isopropylated phenol derivatives having following general formula (VIII). <IMAGE> (VIII) (in the above formula, R1 is a hydrogen or a low alkyl group of C1-C4) A process for producing ortho-isopropylated phenol derivatives (VIII) of the present invention is characterized by obtaining position isomer desired by means of Claisen rearrangement of phenyl allyl ether without catalyst in atmosphere, and then obtaining only one isomer by oxidation and reduction of the above-obtained position isomer. According to the present invention, ortho-alkylated phenol derivatives (VIII) having high purity at low temperature and low pressure can be prepared without producing a by-product and requirement of the complicated separation procedure.
申请公布号 US5414156(A) 申请公布日期 1995.05.09
申请号 US19940245091 申请日期 1994.05.10
申请人 DONG KOOK PHARMACEUTICAL CO., LTD.;KWON, KI-BEOM 发明人 CHO, JUNG H.;NAM, KIE H.;KIM, WAN S.
分类号 C07C37/00;C07C37/055;C07C37/48;C07C39/06;C07C45/40;C07D307/83;(IPC1-7):C07C37/50;C07C37/11 主分类号 C07C37/00
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