METHOD FOR TREATING AND INHIBITING GASTRIC AND DUODENAL ULCERS

摘要

A method for treating and/or inhibiting gastric and duodenal ulcers, comprising administering a pharmaceutical composition comprising an oligosaccharide of the following formula (I): (NeuAc- alpha (2-3)-pGal- beta (1)-(-X-)m-(-Y-)n-)p-Z wherein X is a chemical bond or a group capable of linking the p galactose to either the linking group Y or the multivalent support Z; wherein the C1 glycosidic oxygen of galactose may be replaced by N, S or C; Y is a linking group; Z is a multivalent support; m is 0 or 1; n is 0 or 1; and p is an integer of 2-1,000 is described. Also described is a method for treating and/or inhibiting gastric and duodenal ulcers, comprising administering a pharmaceutical composition comprising an oligosaccharide of the formula (II): NeuAc- alpha (2-3)-pGal- beta (1)-A wherein A is a group capable of bonding to the p galactose; wherein the C1 glycosidic oxygen of galactose may be replaced by N, S or C.