| 摘要 |
PURPOSE: To obtain a skin external agent highly improved in the safety of theα-tocopheryl retinoate therein and capable of adequately presenting its effect, formulated with anα-tocopheryl retinoate and at least one kind of neutral amino acid. CONSTITUTION: This skin external agent contains pref. >=0.001wt.% (esp. 0.01-2.0wt.%) of anα-tocopheryl retinoate and pref. 0.001-10wt.% of at least one kind of neutral amino acid (glycine, alanine, serine, leucine, phenylalanine, proline, and/or hydroxyproline). Theα-tocopheryl retinoate is effective for preventing or treating keratosis etc., and preventing or remedying skin aging.
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