2-(3-Phenylpropyl)hydrazines, intermediates in and a process for the preparation thereof, and their use as medicaments

摘要

The present invention relates to 2-[3-phenyl-3-(phenoxy)propyl]hydrazines of formula I wherein R is hydrogen or loweralkyl; R1 is hydrogen, loweralkyl, arylloweralkyl, a group of the formula wherein R2 is loweralkyl, or a group of the formula wherein R3 is hydrogen, loweralkyl, aryl, or arylloweralkyl; X and Y are hydrogen, loweralkyl, loweralkoxy, halogen, or trifluoromethyl; m and n are independently 1 or 2; the optical isomers thereof; or the pharmaceutically acceptable acid addition salts thereof, which are useful for treating personality disorders such as obsessive compulsive disorders. This invention relates further to intermediates in and a process for the preparation of the compounds of formula I.