| 摘要 |
Compounds of formula I (See Fig. I) in which R1 denotes hydrogen, lower alkyl, lower alkenyl, cycloalkyl, cycloalkenyl, an optionally substituted monocyclic or bicyclic aryl, an optionally substituted hetaryl, an optionally substituted arylalkyl or one of the groups -OR2, -NR3R4 W denotes nitrogen or ~CR5 X,Y,Z independently of one anther denote nitrogen or the group ~CH and in the case that W denotes the group ~CR5 and X denotes the ~CH, Y cannot be the ~CH group A denotes oxygen, ~NR2 or ~N-P n denotes 0-5 P denotes a protecting group for amines such as acetyl, tert.-butyloxycarbonyl or benzyloxycarbonyl R2 denotes hydrogen, lower alkyl or arylalkyl R3,R4 independently of one another denote hydrogen or lower alkyl or together with the nitrogen atom to which they are bound form a five or six-membered heterocyclic ring R5 denotes hydrogen or a group OR2, processes for the production thereof as well as pharmaceutical agents containing these compounds for the treatment of diseases which are the result of thromboembolytic events.
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