摘要 |
<p>The invention is concerned with the compounds having formula (I) the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein Y is CH or N; R1, R2 and R3 each independently are hydrogen or C1-4alkyl; R4 and R5 each independently are hydrogen, halo, C1-4alkyl, C1-4alkyloxy, hydroxy, trifluoromethyl, trifluoromethyloxy or difluoromethyloxy; R6 is C1-4alkyl; or phenyl optionally substituted with halo, C1-4alkylcarbonylamino, C1-4alkyloxy, C1-4alkyl or nitro; Z is C=O or CHOH; and (1) is a radical of formula ((a-1), (a-2), (a-3), (a-4), (a-5), (a-6), or (a-7). Compositions comprising said compounds, processes for preparing the same and the use of these compounds as a medicine.</p> |