发明名称 SULFONAMIDE DERIVATIVES OF AZOLONES ANTI-HELICOBACTER AGENTS.
摘要 <p>The invention is concerned with the compounds having formula (I) the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein Y is CH or N; R1, R2 and R3 each independently are hydrogen or C1-4alkyl; R4 and R5 each independently are hydrogen, halo, C1-4alkyl, C1-4alkyloxy, hydroxy, trifluoromethyl, trifluoromethyloxy or difluoromethyloxy; R6 is C1-4alkyl; or phenyl optionally substituted with halo, C1-4alkylcarbonylamino, C1-4alkyloxy, C1-4alkyl or nitro; Z is C=O or CHOH; and (1) is a radical of formula ((a-1), (a-2), (a-3), (a-4), (a-5), (a-6), or (a-7). Compositions comprising said compounds, processes for preparing the same and the use of these compounds as a medicine.</p>
申请公布号 MX9700340(A) 申请公布日期 1997.05.31
申请号 MX19970000340 申请日期 1995.07.05
申请人 JANSSEN PHARMACEUTICA N. V. 发明人 JAN HEERES;RAYMOND ANTOINE STOKBROEKX;JOSEPH HECTOR MOSTMANS;LOUIS JOZEF ELIZABETH VAN DER VEKEN
分类号 A61K31/41;A61K31/415;A61K31/44;A61K31/495;A61K31/50;A61K31/505;A61P1/00;A61P1/04;A61P31/04;C07D233/70;C07D249/12;C07D401/04;(IPC1-7):C07D401/04 主分类号 A61K31/41
代理机构 代理人
主权项
地址