| 摘要 |
The invention relates to a method for producing a porous material from a liquid solution including a biocompatible polymer. In certain embodiments of the methods, the biocompatible polymer solution is optionally gelled, then frozen in a controlled fashion. The freezing optionally comprises steps that include: rapidly dropping the temperature to between -10°C and -50°C, so as to form a thin layer of frozen biocompatible polymer gel/solution on the thermally conducting surface; (ii) rapidly raising the temperature of the cooling device, to a temperature below sample Tm; (iii) lowering the temperature of the cooling device so as to induce a constant unidirectional growth rate of ice-crystals, then freeze drying the product. |
