Vaccine delivery system and shelf-stable precursor solution for remote encapsulation of active ingredients

摘要

PCT No. PCT/US94/02053 Sec. 371 Date Jan. 2, 1996 Sec. 102(e) Date Jan. 2, 1996 PCT Filed Feb. 25, 1994 PCT Pub. No. WO94/18950 PCT Pub. Date Sep. 1, 1994A method for preparation of a shelf-stable precursor solution used to prepare a vaccine delivery system and useful for remote encapsulation of active ingredients is described. The vaccine delivery system utilizes solvent dilution microcarriers into which pathogen subunits are incorporated for delivering antigens to mucosal sites for stimulating imunoglobulin production.