| 发明名称 |
Cationic lipids for gene therapy |
| 摘要 |
<p>This invention provides novel cationic lipids, particularly guanidino lipids, and methods for their preparation. Also provided are polyanionic-lipid complexes comprising the lipids of the invention, their preparation and use to deliver biologically active substances, particularly nucleic acids to cells.</p> |
| 申请公布号 |
EP0846680(A1) |
申请公布日期 |
1998.06.10 |
| 申请号 |
EP19970117934 |
申请日期 |
1997.10.16 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BELLONI, PAULA NANETTE;HIRSCHFELD, DONALD ROY;NESTOR JR., JOHN JOSEPH;PELTZ, GARY ALLEN |
| 分类号 |
C12N15/09;A61K47/46;A61K47/48;C07C237/06;C07C279/14;C07C279/22;C07C279/24;C07C317/44;C07C323/52;C07D233/30;C07H21/00;(IPC1-7):C07C279/12 |
主分类号 |
C12N15/09 |
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