| 摘要 |
An alkylenediamine derivative or a salt thereof expressed by the following formula 1: <IMG> wherein each of R1 and R2 represents a lower alkyl group, and W represents a group expressed by any of the following formulas 2 to 4; <IMG> <IMG> <IMG> wherein R3 is an alkenyl group; R4 is a lower alkyl group, a lower alkoxy group, or a halogen atom; X is a group expressed by -O-, -S-, or -N(R5)-, while R5 is hydrogen atom, a lower alkyl group, or an alkenyl group; Y is carbon or nitrogen atom; m is an integer of 1 to 3; n is an integer of 0 to 2; R6 is a lower alkyl group; R7 is hydroxy or benzyloxy group; R8 is a lower alkyl, a lower alkoxy, a piperidinoalkyl, a substituted carbamoyl, or a substituted amino group; and 1 is l or 2. The alkylenerdiamine derivative has an anti-ulcer effect or an antibacterial activity against Helicobacter pyroli, and has also high safety to be available f or prevention or cure of ulcers.
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