TROMETAMINIC SALT OF (+)-(S)-2-(3-BENZOYLPHENYL)PROPIONIC ACID, METHOD OF PREPARING THEREOF, AND PHARMACEUTICAL COMPOSITION

摘要

FIELD: pharmaceutical industry. SUBSTANCE: present invention describes trometaminic salt of (+)-(S)- 2-(3-benzoylphenyl) propionic acid of formula I: , method of preparing thereof and using in pharmaceutical composition having anesthetic effect. Salt of formula I is prepared by treatment corresponding substituted propionic acid with trometamine H2NC(CH2OH)3 in polar solvent or in mixture of polar solvents form OC to boiling temperature for 1-24 hours. EFFECT: improved properties of the pharmaceutical composition. 7 cl, 2 ex, 2 tbl