发明名称 |
BIOMATERIALS FOR PREVENTING POST-SURGICAL ADHESIONS COMPRISED OF HYALURONIC ACID DERIVATIVES |
摘要 |
A composite biomaterial (I) for preventing surgical tissue adhesions comprises at least one hyaluronic acid (HA) deriv. selected from (a) benzyl esters of HA in which 75-100% of the COOH gps. of HA are esterified with benzyl and up to 25% are esterified with 10-20C alkyl, provided that at least 80% of the COOH gps. are esterified; and (b) self-crosslinked HA derivs., in which 0.5-20% of the COOH gps. of HA are crosslinked to OH gps. of the same or different HA molecules. Also claimed is the use of (I) for preventing surgical adhesions and a method for preventing tissue adhesions using (I). |
申请公布号 |
HU9903446(A2) |
申请公布日期 |
2000.02.28 |
申请号 |
HU19990003446 |
申请日期 |
1996.08.29 |
申请人 |
Fidia Advanced Biopolymers S.r.l. |
发明人 |
CALLEGARO, LANFRANCO;PAVESIO, ALESSANDRA;PRESSATO, DANIELE |
分类号 |
A61L31/00;A61L17/00;A61L31/04;A61L31/06;A61L31/10;A61L31/12;A61P41/00 |
主分类号 |
A61L31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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