摘要 |
<p>Crystalline paroxetine hydrochloride propan-2-ol solvate having a modified habit that is more easily desolvated to form the anhydrate is obtained by crystallising from a solution of paroxetine hydrochloride in propan-2-ol under intense insonation conditions, or in a continuous crystalliser, or which has been seeded with crystals of a paroxetine hydrochloride solvate or anhydrate, especially Form A anhydrate.</p> |