| 摘要 |
The new substituted pyrimidon and pyridon compounds are effective for the prevention and treatment of diseases running with the mediation of TNF-alpha,IL-1beta, IL-6 and/or IL-6, and/or IL-8, as well as for easying of pains and in diabetes. The invention relates to new compounds, to their analogues, promedicamentous forms and their pharmaceutically acceptable salts, to pharmaceutical compositions and methods for the prevention and treatment of diseases and other sufferings or conditions occurring with inflammations, pains, diabetes, and others. The invention also relates to methods for the preparation of the compounds and to intermediate products for their preparation. 46 claims |
