发明名称 Amyloid skanning som en surrogatmarkør for anti-amyloide behandlingsformers effektivitet
摘要 The present method for determining the efficacy of therapy in the treatment of amyloidosis involves administering to a patient in need thereof a compound of formula (I) or Formula (II) or structures 1-45 and imaging the patient. After said imaging, at least one anti-amyloid agent is administered to said patient. Then, an effective amount of a compound of formula (I) or Formula (II) or structures 1-45 is administered to the patient and the patient is imaged again. Finally, baseline levels of amyloid deposition in the patient before treatment with the anti-amyloid agent are compared with levels of amyloid deposition in the patient following treatment with the anti-amyloid agent.
申请公布号 NO339187(B1) 申请公布日期 2016.11.14
申请号 NO20070000593 申请日期 2007.01.31
申请人 UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 发明人 MATHIS JR CHESTER A;KLUNK WILLIAM E
分类号 A61K51/04;A61P25/28 主分类号 A61K51/04
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