发明名称 |
ANALOGUES OF INSULIN-LIKE GROWTH FACTOR-1 (IGF-1) HAVING AMINO ACID SUBSTITUTION AT POSITION 59 59 1(IGF-1) |
摘要 |
The present invention relates to novel analogues of insulin-like growth factor-1 (IGF-1), pharmaceutical compositions containing said analogues, and the use of said analogues for treatment of IGF-1-receptor mediated conditions, such as short stature, diabetes therapy, neurodegenerative disease treatment, and cartilage repair. More particularly, the present invention relates to novel analogues of IGF-1 having an amino acid substitution at position 59, e.g., (Asn59)hIGF-1(1-70)-OH (SEQ ID NO:1), and other substitution(s) as defined herein. |
申请公布号 |
HK1170748(A1) |
申请公布日期 |
2016.12.02 |
申请号 |
HK20120111503 |
申请日期 |
2012.11.13 |
申请人 |
IPSEN PHARMA S.A.S. |
发明人 |
DONG, Zheng, Xin;PRAIRIE, Nicholas, C.;UFRET, Maria, L.;ZHANG, Jundong;ROTHMAN, Deborah;COMSTOCK, Jeanne, Mary |
分类号 |
C07K |
主分类号 |
C07K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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