发明名称 |
2-ARYLETHENYL CARBAPENEM DERIVATIVES AND PROCESS FOR PREPARING THE SAME |
摘要 |
PURPOSE: Provided are 2-arylethenyl carbapenem derivative of the formula(1) and its pharmaceutically acceptable salt which have therapeutic effect in methicillin resistant staphylococcus aureus(MRSA) infection. And its manufacturing method and an antibacterial composition containing it as an active ingredient are also provided. CONSTITUTION: 2-arylethenyl carbapenem derivative is represented by the formula(1), wherein R is halogen, nitro, hydroxy or cyano substituted phenyl or fused aryl group; or halogen or C1-3 alkyl group substituted monocyclic, bicyclic or tricyclic 5 or 6 membered hetero aryl group containing at least one of O, S or N atom; and M is hydrogen or zwitterion forming pharmaceutically acceptable salts.
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申请公布号 |
KR20020006889(A) |
申请公布日期 |
2002.01.26 |
申请号 |
KR20000040396 |
申请日期 |
2000.07.14 |
申请人 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY |
发明人 |
JUNG, HUI JEONG;JUNG, WON JANG;KIM, BONG JIN;KIM, EUN JEONG;KIM, JAE HAK;KWAK, HYEON JEONG;LEE, CHEOL HAE;PYUN, DO GYU;SONG, SIN SEOP |
分类号 |
C07D205/08;(IPC1-7):C07D205/08 |
主分类号 |
C07D205/08 |
代理机构 |
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地址 |
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