发明名称 |
Selective PI3K delta inhibitors |
摘要 |
The present invention relates to selective inhibitors of PI3K delta protein kinases, methods of preparing them, pharmaceutical compositions containing them and methods of treatment and/or prevention of kinase mediated diseases or disorders with them. |
申请公布号 |
US9475818(B2) |
申请公布日期 |
2016.10.25 |
申请号 |
US201514832962 |
申请日期 |
2015.08.21 |
申请人 |
RHIZEN PHARMACEUTICALS SA |
发明人 |
Vakkalanka Swaroop Kumar V. S.;Muthuppalaniappan Meyyappan;Nagarathnam Dhanapalan |
分类号 |
C07D487/04;A61K31/519;A61P35/00;A61K45/06 |
主分类号 |
C07D487/04 |
代理机构 |
Blank Rome LLP |
代理人 |
Blank Rome LLP |
主权项 |
1. A compound selected from
(S)-2-(1-(4-amino-3-(3-fluoro-4-isopropoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-3-(3-fluorophenyl)-4H-chromen-4-oneand pharmaceutically acceptable salts thereof. |
地址 |
La Chaux-de-Fonds CH |