发明名称 |
Photoimmunotherapies for cancer using photosensitizer immunoconjugates and combination therapies |
摘要 |
The present invention relates to photosensitizer immunoconjugate compositions and combination therapies for use in cancer related photodynamic treatments and diagnostic methods. Photosensitizer immunoconjugates comprising a photosensitizer conjugated to a tumor-specific and/or tumoricidial antibody and processes for the preparation thereof are described. The use of photosensitizer immunoconjugates (PICs) offers improved photosensitizer delivery specificity for diagnostic and therapeutic applications. Combination therapies to co-localize activated photosensitizer compounds and tumoricidal antibodies in tumor tissues are also described. |
申请公布号 |
AU2002348477(A1) |
申请公布日期 |
2002.12.23 |
申请号 |
AU20020348477 |
申请日期 |
2002.05.01 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
MARK D. SAVELLANO;TAYYABA HASAN;MIHAELA SKOBE |
分类号 |
A61K41/00;C07K16/28;C12P21/08;(IPC1-7):A61K39/395;A61K39/44 |
主分类号 |
A61K41/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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