发明名称 Isoprenoid analog compounds and methods of making and use thereof
摘要 The invention provides compounds of formula I: wherein X, R1, R2, and n have any of the values defined in the specification, and their pharmaceutically acceptable salts. The compounds are useful, for example, for blocking prenylation transferase enzymes, for probing or diagnosing protein prenylation processes, and for treating cancer in a mammal. The invention also provides pharmaceutical compositions, processes for preparing compounds of formula I, and intermediates useful for the synthesis of compounds of formula I.
申请公布号 US2003022869(A1) 申请公布日期 2003.01.30
申请号 US20020116737 申请日期 2002.04.03
申请人 WIEMER DAVID;HOHL RAYMOND J. 发明人 WIEMER DAVID;HOHL RAYMOND J.
分类号 A61K49/00;C07F9/09;C07F9/113;C07F9/38;C07F9/40;(IPC1-7):A61K49/00;A61K31/66;C07F9/02 主分类号 A61K49/00
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