发明名称 Skin lightening compositions
摘要 This invention relates to compositions, compounds, and methods for lightening skin, using active compounds having the general structure:wherein each X is halo; m is 1 to 4; each R' and R'' is independently selected from hydrogen, halo, C1-C10 alkyl, substituted C1-C10 alkyl, substituted or unsubstituted phenyl, substituted or unsubstituted naphthyl, OR, OCOR, OCRROR, COR, CR(OR)OR, CONRR, COOR, CRROR, CN, SR, and NRR; each R is selected from hydrogen, C1-C10 alkyl, substituted C1-C10 alkyl, substituted or unsubstituted phenyl, and substituted or unsubstituted naphthyl; n is 1 to 5; Z is O; in an amount effective to lighten skin; and a pharmaceutically-acceptable carrier therefor.
申请公布号 US6537527(B1) 申请公布日期 2003.03.25
申请号 US19980133861 申请日期 1998.08.13
申请人 CHILDREN'S HOSPITAL MEDICAL CENTER 发明人 KVALNES KALLA LYNN;DELONG MITCHELL ANTHONY;BRADBURY BARTON JAMES;MOTLEY CURTIS BOBBY;CARTER JOHN DAVID
分类号 A61K8/30;A61K8/00;A61K8/11;A61K8/33;A61K8/34;A61K8/368;A61K8/37;A61K8/41;A61K8/42;A61K8/44;A61K8/46;A61K8/49;A61K8/55;A61Q17/04;A61Q19/00;A61Q19/02;C07C41/48;C07C41/54;C07C43/315;C07D307/20;C07D309/10;C07D309/12;C07D333/32;C07D335/02;(IPC1-7):A61K7/48;A61K31/03 主分类号 A61K8/30
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