发明名称 Substituted pyridoindoles as serotonin agonists and antagonists
摘要 The present invention is directed to certain novel compounds represented by structural Formula (I)or pharmaceutically acceptable salt forms thereof, wherein R<1>, R<5>, R<6>, R<7>, R<8>, R<9>, X, b, k, and n, and the dashed lines are described herein. The invention is also concerned with pharmaceutical formulations comprising these novel compounds as active ingredients and the use of the novel compounds and their formulations in the treatment of certain disorders. The compounds of this invention are serotonin agonists and antagonists and are useful in the control or prevention of central nervous system disorders including obesity, anxiety, depression, psychosis, schizophrenia, sleep disorders, sexual disorders, migraine, conditions associated with cephalic pain, social phobias, and gastrointestinal disorders such as dysfunction of the gastrointestinal tract motility.
申请公布号 US6699852(B2) 申请公布日期 2004.03.02
申请号 US20010026611 申请日期 2001.12.19
申请人 BRISTOL-MYERS SQUIBB PHARMA COMPANY 发明人 ROBICHAUD ALBERT;FEVIG JOHN M.;MITCHELL IAN S.;LEE TAEKYU;CHEN WENTING;CACCIOLA JOSEPH
分类号 C07D513/00;A61K31/551;A61K31/553;A61K31/554;A61P1/00;A61P3/04;A61P25/00;A61P25/06;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P43/00;C07D471/16;C07D498/16;C07D513/16;(IPC1-7):A61K31/33;A61K31/55;C07D245/00;C07D267/02;C07D223/14 主分类号 C07D513/00
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