发明名称 |
Compositions and methods for inhibiting bone resorption |
摘要 |
The present invention relates to oral compositions and methods for inhibiting bone resoprtion in a mammal while counteracting the occurrence of potentially adverse gastrointestinal effects. The compositions useful herein comprise the combination of a pharmaceutically effective amount of a nitrogen-containing bisphosphonate or a pharmaceutically-acceptable salt thereof and a pharmaceutically effective amount of an isoprenoid compound.
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申请公布号 |
US6699850(B2) |
申请公布日期 |
2004.03.02 |
申请号 |
US20010029678 |
申请日期 |
2001.12.21 |
申请人 |
MERCK & CO., INC. |
发明人 |
RESZKA ALFRED A.;SCOLNICK EDWARD S. |
分类号 |
A61K31/01;A61K31/045;A61K31/075;A61K31/133;A61K31/22;A61K31/66;A61K31/663;A61K31/675;A61P19/10;A61P43/00;(IPC1-7):A61K31/66 |
主分类号 |
A61K31/01 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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