| 摘要 |
Disclosed are compounds of the formula:wherein R<13 >represents an imidazole ring; R<14 >represents a carbamate, urea, amide or sulfonamide group; R<8 >represents H when the alkyl chain between the amide group and the R<13 >imidazole group is substituted, or R<8 >represents a substituent such as arylalkyl, heteroarylalkyl or cycloalkyl; and the remaining substituents are as defined herein.Also disclosed are compounds wherein R<8 >is H, and the alkyl chain between the amide group and the R<13 >imidazole group is unsubstituted.Also disclosed is a method of treating cancer and a method of inhibiting farnesyl protein transferase using the disclosed compounds.
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