METHOD OF IDENTIFYING PEPTIDES CAPABLE OF BINDING TO MHC MOLECULES, PEPTIDES IDENTIFIED THEREBY AND THEIR USES
摘要
A method of identifying peptides originating from a particular cell type and being capable of binding to MHC molecules of a particular haplotype is disclosed. The method comprises obtaining a cell type expressing a soluble and secreted form of the MHC molecules of the particular haplotype; collecting the soluble and secreted form of the MHC molecules of the particular haplotype; and analyzing peptides bound to the soluble and secreted form of the MHC molecules of the particular haplotype, thereby identifying the peptides originating from the particular cell type and being capable of binding to MHC molecules of the particular haplotype.
申请公布号
WO02094981(A3)
申请公布日期
2004.09.10
申请号
WO2002IL00383
申请日期
2002.05.16
申请人
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.;BARNEA, EILON;BEER, ILAN;ZIV, TAMAR;ADMON, ARIE;DASSAU, LIOR;BUCHSBAUM, SAMUEL
发明人
BARNEA, EILON;BEER, ILAN;ZIV, TAMAR;ADMON, ARIE;DASSAU, LIOR;BUCHSBAUM, SAMUEL