发明名称 PYRIDINE DERIVATIVES WITH IKB-KINASE (IKK-bgr;) INHIBITING ACTIVITY.
摘要 <p>Pyridine compounds of general formula (I) wherein -R1 represents, or in which R11 is hydrogen, C1-6 alkyl, halogen, hydroxy, C1-12 alkoxy, nitro, amino, C1-6 alkylsulfonylamino, C1-6 alkoxycarbonyl, C1-6 alkylamino, di (C1-6 alkyl)amino, C1-6 alkanoylamino, phenyl C1-6 alkylamino, phenylsulfonylamino, or -O-(CH2)n-R111 ; R2 represents hydrogen or halogen; R3 represents hydrogen, -CR31R32R33, or -NR34R35; R4 is hydrogen, carbamoyl, CN, carboxyl, etc.; R5 is amino, C1-6 alkylamino, di C1-6 alkylamino, etc. or salt thereof. The compound has an excellent anti-inflammatory activity, and other biological activity.</p>
申请公布号 MXPA03002491(A) 申请公布日期 2004.12.06
申请号 MX2003PA02491 申请日期 2001.09.10
申请人 BAYER AKTIENGESELLSCHAFT 发明人 FUCHIKAMI, KINJI
分类号 A61K31/437;A61K31/4375;A61K31/4418;A61K31/4427;A61K31/443;A61K31/4433;A61K31/4545;A61K31/4709;A61K31/496;A61K31/519;A61K31/5365;A61K31/551;A61P1/04;A61P9/10;A61P11/02;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P19/06;A61P21/00;A61P27/02;A61P29/00;A61P31/00;A61P35/00;A61P37/02;A61P37/06;A61P43/00;C07D213/08;C07D213/09;C07D213/10;C07D213/73;C07D213/80;C07D213/85;C07D401/04;C07D401/06;C07D401/12;C07D401/14;C07D405/14;C07D409/12;C07D409/14;C07D413/14;C07D471/04;C07D471/18;C07D498/04;C07D513/04;C07D521/00;(IPC1-7):A61K31/435;A61K31/442 主分类号 A61K31/437
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