Medical image processor and storage medium

摘要

A medical image processor and storage medium are shown. According to one implementation, a medical image processor includes an input unit, an operation unit, a cell nucleus extracting unit, a fluorescent bright point extracting unit, a feature amount calculating unit, and an output unit. The input unit is used to input a cell shape image showing a shape of a cell and a fluorescent image showing expression of a specific protein as a fluorescent bright point. The operation unit is used to specify an analysis target region. The cell nucleus extracting unit extracts a region of a cell nucleus. The fluorescent bright point extracting unit extracts a fluorescent bright point. The feature amount calculating unit calculates a feature amount showing an expression amount of the specific protein. The output unit outputs the calculated feature amount.

主权项

1. A medical image processor comprising:
an input unit to input a cell shape image showing a shape of a cell in a tissue slice and a fluorescent image showing expression of a specific protein in the tissue slice as a fluorescent bright spot, the fluorescent image being obtained using a fluorescent substance included nanoparticle, which has an average particle diameter in the range including 30 nm to 800 nm; an operation unit to specify an analysis target region from the cell shape image; a cell nucleus extracting unit which extracts a region of a cell nucleus from the cell shape image; a fluorescent bright point extracting unit which extracts a fluorescent bright point showing expression of the specific protein from the fluorescent image; a feature amount calculating unit which calculates a feature amount showing an expression amount of the specific protein in the specified analysis target region based on the extracted cell nucleus region in the analysis target region specified with the operation unit and the fluorescent bright point; and an output unit which outputs the calculated feature amount, wherein the florescent substance included nanoparticle is a nanoparticle with a fluorescent substance dispersed inside, the feature amount calculating unit obtains information of a number of fluorescent bright points and a number of cell nuclei in the analysis target region specified with the operation unit, and based on the obtained number of cell nuclei and the number of fluorescent bright points, the feature amount calculating unit calculates the feature amount showing the expression amount of the specific protein in the specified analysis target region, and the feature amount calculating unit calculates a number of the fluorescent bright points in each cell nucleus in the specified analysis target region as the feature amount showing the expression amount of the specific protein, and wherein the florescent bright point extracting unit extracts the fluorescent bright spot showing expression of the specific protein from the fluorescent image using an immunohistochemical (IHC) method.