| 发明名称 |
Regulated apoptosis |
| 摘要 |
We have developed a general procedure for the regulated (inducible) dimerization or oligomerization of intracellular proteins and disclose methods and materials for using that procedure to regulatably initiate cell-specific apoptosis (programmed cell death) in genetically engineered cells
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| 申请公布号 |
US6891021(B2) |
申请公布日期 |
2005.05.10 |
| 申请号 |
US20010054712 |
申请日期 |
2001.11.13 |
| 申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
CRABTREE GERALD R.;SCHREIBER STUART L.;SPENCER DAVID M.;WANDLESS THOMAS J.;BELSHAW PETER |
| 分类号 |
A61K38/00;A61K47/48;C07D498/18;C07F5/02;C07H19/01;C07K7/64;C07K14/395;C07K14/705;C07K14/71;C07K14/725;C12N15/62;C12N15/63;C12P15/00;(IPC1-7):C07K2/00;C07K4/00 |
主分类号 |
A61K38/00 |
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