| 摘要 |
Disclosed herein are .alpha.-Hydroxy sulfonate aldehydes and synthesis metho ds therefor. Germicidal compositions including the .alpha.-hydroxy sulfonate aldehydes, are also disclosed. In one aspect, a germicidal composition may include a diluent, an d a germicidally effective amount of a water-soluble germicidal compound includi ng an aldehyde group and an .alpha.-hydroxy sulfonate group. The water-soluble compound may have a solubility of at least 5 (w/v)% in water. In a further aspect, the compound may include 1-hydroxy-3-oxo-2-phenyl-propane-1-sulfonic acid salt, (2-formyl- phenyl)- hydroxy-methane sulfonic acid salt, 1-hydroxy-2-(4-methanesulfonyl-2-nitro- phenyl)-3- oxo-propane-1-sulfonic acid salt, 2-bromo-1-hydroxy-3-oxo-propane-1-sulfonic acid salt, 2-chloro-1-hydroxy-3-oxo-propane-1-sulfonic acid salt, 2-(1-formyl-2-hydroxy -2- sulfo- ethyl)-isonicotinic acid salt, 2-benzooxazol-2-yl-1-hydroxy-3-oxo-propane-1- sulfonic acid salt, or 1-hydroxy-2-(4-methoxy-phenyl)-3-oxo-propane-1-sulfonic acid salt. Germicidal compositions including a mixture of an a-hydroxy sulfonate aldehy de and one or more phthalaldehydes, such as phthalaldehyde, isophthalaldehyde, terephthalaldehyde, or a combination thereof, are also disclosed. Methods of using the compounds or compositions for killing bacteria, disinfection, or sterilization, are also disclosed.
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