Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use

摘要

Disclosed is the use of at least one HCV envelope E1 protein or part thereof, for the preparation of a prophylactic vaccine, administered prior to infection with a challenge HCV infection, to prevent evolution to chronic infection of a challenge HCV infection, wherein the HCV envelope E1 protein or part thereof is a single or specific oligomeric protein not disulphide linked to other contaminants.