| 发明名称 |
NOVEL PYRIMIDINE-4,6-DICARBOXAMIDES FOR THE SELECTIVE INHIBITION OF COLLAGENASES |
| 摘要 |
Pyrimidine-4,6-dicarboxamides of formula (I), are suitable for the selective inhibition of collagenase (MMP 13). The pyrimidine-4,6-dicarboxamides can thus be used for the treatment of degenerative joint diseases. |
| 申请公布号 |
PL375044(A1) |
申请公布日期 |
2005.11.14 |
| 申请号 |
PL20030375044 |
申请日期 |
2003.10.18 |
| 申请人 |
SANOFI-AVENTIS DEUTSCHLAND GMBH |
发明人 |
KLINGLER OTMAR;KIRSCH REINHARD;HABERMANN JOERG;WEITHMANN KLAUS-ULRICH;ENGEL CHRISTIAN;PIRARD BERNARD |
| 分类号 |
A61P19/00;C07D239/28;C07D401/12;C07D403/12;C07D405/12;C07D405/14;C07D409/14;C07D413/12;C07D413/14;C07D471/04 |
主分类号 |
A61P19/00 |
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