发明名称 СРЕДСТВО ДЛЯ ПРОФИЛАКТИКИ ИЛИ ЛЕЧЕНИЯ НЕВРОПАТИИ
摘要 The present invention provides an agent for preventing or treating neuropathy having superior action and low toxicity. This agent comprises a compound represented by the formula: wherein ring A is a 5-membered aromatic heterocycle containing 2 or more nitrogen atoms, which may further have substituent(s); B is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group; X is a divalent acyclic hydrocarbon group; Z is -O-, -S-, -NR<SUB>2</SUB>-, -CONR<SUB>2</SUB>- or -NR<SUB>2</SUB>CO- (R<SUB>2 </SUB>is a hydrogen atom or an optionally substituted alkyl group); Y is a bond or a divalent acyclic hydrocarbon group; R<SUB>1 </SUB>is an optionally substituted cyclic group, an optionally substituted amino group or an optionally substituted acyl group, provided that when the 5-membered aromatic heterocycle represented by ring A is imidazole, then Z should not be -O-, or a salt thereof.
申请公布号 RU2005116689(A) 申请公布日期 2006.01.20
申请号 RU20050116689 申请日期 2003.10.30
申请人 ТАКЕДА ФАРМАСЬЮТИКАЛ КОМПАНИ ЛИМИТЕД (JP) 发明人 МОМОСЕ Йю (JP);САКАИ Нозому (JP);МАЕКАВА Цуйоси (JP);ХАЗАМА Масатоси (JP);КАВАМУРА Тору (JP);СЕРА Мисайо (JP)
分类号 C07D417/10;A61K31/402;A61K31/415;A61K31/4155;A61K31/416;A61K31/4174;A61K31/4178;A61K31/4184;A61K31/427;A61K31/4439;A61K31/66;C07D231/12;C07D401/12;C07D403/12;C07D413/12;C07D417/12;C07F9/40;C07F9/553;C07F9/6503;C07F9/6506;C07F9/6518;C07F9/653;C07F9/6539;C07F9/6558;C07F9/6571 主分类号 C07D417/10
代理机构 代理人
主权项
地址