| 摘要 |
FIELD: medicine, pharmacy, pharmacology. ^ SUBSTANCE: invention relates to a pharmaceutical composition comprising the medicinal preparation afobasol as an active component. Indicated pharmaceutical composition is prepared as a tablet formulation and comprises medicinal preparation afobasol, i. e. 5-ethoxy-2-[2-(morpholino)ethylthio]benzimidazole hydrochloride, eliciting the expressed anxiolytic activity in the broad range of doses. The composition comprises small amounts of special additives, such as lactose, starch, polyvinylpyrrolidone, stearic acid or stearate. Invention provides easy release of active component that provides its high bioavailability. Tablets satisfy all requirements of the State Pharmacopoeia of XI edition. ^ EFFECT: improved and valuable pharmaceutical and medicinal properties of pharmaceutical composition. ^ 8 cl, 1 tbl, 3 ex |
