PROCESS FOR THE PREPARATION OF ANILINE DERIVATIVES OF NICOTINIC ACID AND SALTS THEREOF

摘要

Aniline derivs. of nicotinic acid, analgesics anti-inflammatories. Cpds. of formula (I) and salts, (where R1 = H, CO2H, CO2-, COOR5, CN, CONH2 CONHNH2; R2 = H, halogen, NO2, SO2, SO2NH2, NHR5, NR25, NHCOR5, OR5 or NH2; R5 = alkyl, alkaryl, or aryl; R3 and R4 = H, halogen, CN, OH, OR5, CO2H, NO2, CH2X, CHX2, or CX3; and X = halogen) are analgesics and antiinflammatories useful in the treatment of rheumatism, polyarthritis phlebitis etc.